Incidence and Cause of Hypertension During Adrenal Radiofrequency Ablation
| Autor: | Kan Takeda, Haruyuki Takaki, Tomomi Yamada, Koichiro Yamakado, M. Kashima, Takashi Yamanaka, Junji Uraki, Atsuhiro Nakatsuka |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Radiofrequency ablation medicine.medical_treatment Adrenal Gland Neoplasms law.invention Risk Factors law Biomarkers Tumor medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Prospective cohort study Aged Hydrocortisone Aged 80 and over Adrenal gland business.industry Incidence Incidence (epidemiology) Middle Aged Ablation Treatment Outcome surgical procedures operative medicine.anatomical_structure Blood pressure Hypertension Catheter Ablation Regression Analysis Female Radiology Cardiology and Cardiovascular Medicine business Complication therapeutics medicine.drug |
| Zdroj: | CardioVascular and Interventional Radiology. 35:1422-1427 |
| ISSN: | 1432-086X 0174-1551 |
| DOI: | 10.1007/s00270-012-0348-6 |
| Popis: | To evaluate the incidence and cause of hypertension prospectively during adrenal radiofrequency ablation (RFA).For this study, approved by our institutional review board, written informed consent was obtained from all patients. Patients who received RFA for adrenal tumors (adrenal ablation) and other abdominal tumors (nonadrenal ablation) were included in this prospective study. Blood pressure was monitored during RFA. Serum adrenal hormone levels including epinephrine, norepinephrine, dopamine, and cortisol levels were measured before and during RFA. The respective incidences of procedural hypertension (systolic blood pressure200 mmHg) of the two patient groups were compared. Factors correlating with procedural systolic blood pressure were evaluated by regression analysis.Nine patients underwent adrenal RFA and another 9 patients liver (n = 5) and renal (n = 4) RFA. Asymptomatic procedural hypertension that returned to the baseline by injecting calcium blocker was found in 7 (38.9%) of 18 patients. The incidence of procedural hypertension was significantly higher in the adrenal ablation group (66.7%, 6/9) than in the nonadrenal ablation group (11.1%, 1/9, P 0.0498). Procedural systolic blood pressure was significantly correlated with serum epinephrine (R (2) = 0.68, P 0.0001) and norepinephrine (R (2) = 0.72, P 0.0001) levels during RFA. The other adrenal hormones did not show correlation with procedural systolic blood pressure.Hypertension occurs frequently during adrenal RFA because of the release of catecholamine. |
| Databáze: | OpenAIRE |
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