Juvenile Xanthogranuloma: An Entity With a Wide Clinical Spectrum
| Autor: | Ligia Aranibar, Pablo Vargas-Mora, M.J. Hernández-San Martín |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Histology Histiocytosis Non-Langerhans-Cell Juvenile xanthogranuloma Biopsy First year of life Dermatology Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences Non-Langerhans cell histiocytosis 0302 clinical medicine Juvenile xanthogranulomas Humans Medicine Skin medicine.diagnostic_test business.industry medicine.disease 030220 oncology & carcinogenesis Histiocytoses Clinical diagnosis Skin biopsy business Large group Xanthogranuloma Juvenile |
| Zdroj: | Actas Dermo-Sifiliográficas (English Edition). 111:725-733 |
| ISSN: | 1578-2190 |
| DOI: | 10.1016/j.adengl.2020.10.007 |
| Popis: | Juvenile xanthogranulomas (JXGs) are rare, benign lesions that belong to the large group of non-Langerhans cell histiocytoses. JXG presents with 1 or more erythematous or yellowish nodules that are usually located on the head or neck. Most JXG lesions are congenital or appear during the first year of life. Extracutaneous involvement is rare, but the literature traditionally suggests investigating the possibility of ocular compromise. JXG is mainly a clinical diagnosis, but a skin biopsy may sometimes be needed for confirmation. JXGs on the skin are self-limiting and usually do not require treatment. This review describes the clinical and therapeutic aspects of JXG, emphasizing available evidence and the diagnosis of extracutaneous involvement. |
| Databáze: | OpenAIRE |
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