Controlling Endemic Pathogens—Challenges and Opportunities
| Autor: | William L James, Sunita S. Shankaran, Maurine R. Hobbs |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Burden of disease Research groups Review/Case Reports 040301 veterinary sciences Parasitic Diseases Animal Animal resource Aquaculture Biology 0403 veterinary science Fish Diseases 03 medical and health sciences Utah Microsporidiosis Animals Animal Husbandry Myxozoa Baseline (configuration management) Environmental planning Zebrafish business.industry Environmental resource management 04 agricultural and veterinary sciences Fish health Core Facility 030104 developmental biology Microsporidia Fish Animal Science and Zoology business Pseudoloma neurophilia Developmental Biology |
| Zdroj: | Zebrafish. 13:S-66 |
| ISSN: | 1557-8542 1545-8547 |
| Popis: | By most measures, the University of Utah Centralized Zebrafish Animal Resource is a successful zebrafish core facility: we house ∼4000-5000 tanks for over 16 research groups; provide services and equipment for ∼150 users; are currently undergoing an expansion by 3000 tanks; and have been praised by institutional and national regulatory agencies for the cleanliness and efficiency of our facility. In recent years, we have implemented new programs to improve the overall health of our colony and believe we have seen a reduction in apparently sick fish. However, there are still deficiencies in our monitoring and pathogen control programs. Our histopathology sample sizes have been insufficient to estimate prevalence, but our sentinel tank program reveals the presence of Pseudoloma neurophilia and myxozoan, presumably Myxidium streisinger, in our facility. As we develop protocols to further reduce the burden of disease, we are focused on defining our baseline, establishing goals, and implementing methods to monitor our progress. The data generated by this approach will allow us to evaluate and implement the most cost-effective protocols to improve fish health. |
| Databáze: | OpenAIRE |
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