A polymorphism in the CYP17 gene is associated with male breast cancer

Autor:	B B Cohen, I E Young, V A Anderson, M L Hooper, C Annink, Kathreena M Kurian, Ian Kunkler, C. M. Steel, Andrew H. Wyllie
Jazyk:	angličtina
Rok vydání:	1999
Předmět:	Adult Male Cancer Research medicine.medical_specialty Genotype Short Communication Mammary gland Breast Neoplasms male breast cancer Biology Breast Neoplasms Male CYP17 polymorphism Internal medicine Epidemiology medicine Humans Genetic variability Allele skin and connective tissue diseases Gene Alleles Aged Aged 80 and over Polymorphism Genetic Case-control study Steroid 17-alpha-Hydroxylase Estrogens Middle Aged medicine.disease medicine.anatomical_structure Endocrinology Oncology Male breast cancer Case-Control Studies Cancer research Androgens Female
Zdroj:	British Journal of Cancer
ISSN:	1532-1827 0007-0920
Popis:	The CYP17 gene codes for the cytochrome P450c17α enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer. © 1999 Cancer Research Campaign
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea9a043f271db0ea5471cc858e3fb7e http://europepmc.org/articles/PMC2374358 Zobrazit plný text záznamu Plný text ve formátu PDF