Comparison of blood pressure response to heat stress in sauna in young hypertensive patients treated with atenolol and diltiazem

Autor: Antti Kohvakka, Olavi J. Luurila, Stig Sundberg
Rok vydání: 1989
Předmět:
Zdroj: The American journal of cardiology. 64(1)
ISSN: 0002-9149
Popis: A sauna bath induces a marked increase in heart rate and a decrease in peripheral vascular resistance as a consequence of heat-induced peripheral vasodilation.1,2 In normotensive patients the heat stress of a sauna does not change blood pressure (BP). However, a decrease in BP is evident in hypertensive patients,3 with a risk of hypotensive symptoms after sauna.1,4 Surprisingly little is known about the impact of cardiovascular drugs on the hemodynamic changes induced by heat stress. Because the β-blocking agent propranolol causes bradycardia, patients are warned of a hypotensive effect after sauna.4 Calcium antagonists may, by peripheral vasodilation, have an additive effect on the dilation induced by heat stress.5,6 However, no studies on this topic have been published. In the present study we compared the hemodynamic changes during and after heat stress caused by sauna bath in young hypertensives treated with the calcium antagonist diltiazem and the β1-selective adrenoceptor antagonist atenolol. We evaluated the possible additive vasodilatory effects of heat stress and calcium antagonists, and the tendency toward hypotensive reactions during and after a sauna bath.
Databáze: OpenAIRE