Echinacea purpurea supplementation stimulates select groups of human gastrointestinal tract microbiota
| Autor: | G. S. Denny, C. E. Cerniglia, J. C. Foote, B. D. Erickson, L. L. Hill |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Pharmacology biology Aerobic bacteria Human gastrointestinal tract Colony Count Microbial Pathogenic bacteria biology.organism_classification Antimicrobial medicine.disease medicine.disease_cause Inflammatory bowel disease Echinacea Microbiology Gastrointestinal Tract medicine.anatomical_structure Dietary Supplements medicine Humans Female Pharmacology (medical) Anaerobic bacteria Bacteroides Bacteroides fragilis |
| Zdroj: | Journal of Clinical Pharmacy and Therapeutics. 31:599-604 |
| ISSN: | 1365-2710 0269-4727 |
| DOI: | 10.1111/j.1365-2710.2006.00781.x |
| Popis: | Summary Background and objective: The objective of this research was to determine the effects of the dietary supplement Echinacea purpurea on aerobic and anaerobic bacteria common to the human gastrointestinal (GI) tract. Botanical extracts have shown in vitro antimicrobial effects against certain pathogenic bacteria. It is uncertain if medicinal herbs have any effect against pathogenic bacteria or on the native GI microbiota. Methods: Fifteen human subjects consumed 1000 mg of standardized E. purpurea for 10 days. Faecal samples were collected at baseline, 10 days and 17–18 days following supplementation. Samples were tested for select aerobic and anaerobic bacteria using plate culture microbiological methods. Results and discussion: Significant increases were found for total aerobic bacteria, Bacteroides group and Bacteroides fragilis after E. purpurea exposure. Supplementation did not significantly alter the number of enteric bacteria, enterococci, lactobacilli, bifidobacteria or total anaerobic bacteria. Conclusion: Echinacea supplementation has altered the GI microbiota. The health consequences associated with this change are unknown but previous research has shown increased Bacteroides concentrations associated with diarrhoea, inflammatory bowel disease and increased risk of colon cancer. Additional research should delineate the role of Echinacea in the stimulation of Bacteroides and describe the effects of other botanical supplements to the GI microbiota. |
| Databáze: | OpenAIRE |
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