Cytopathogenic Effects in a Cell Culture Infected with a Murine Leukemia Virus
| Autor: | M. A. Fink, J. G. Vidrine, Arthur C. Upton, W. W. Harris, Ernestine Teeter, R.L. Tyndall |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
Virus Cultivation
viruses Mouse Leukemia Virus Cell Culture Techniques Fluorescent Antibody Technique Electrons Fluorescence General Biochemistry Genetics and Molecular Biology Inclusion bodies Microbiology Tissue Culture Techniques Mice Tissue culture Murine leukemia virus Animals Microscopy biology Research biochemical phenomena metabolism and nutrition biology.organism_classification Staining Leukemia Virus Murine Microscopy Electron Microscopy Fluorescence Cell culture Oncogenic Viruses Oncovirus |
| Zdroj: | Experimental Biology and Medicine. 119:186-189 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-119-30132 |
| Popis: | SummaryCell cultures grown in modified NCTC 109 medium and infected with the Rauscher leukemia virus showed CPE when subcultured in Eagle's basal medium. Non-infected control cultures treated in a similar manner showed no CPE. The CPE in infected cultures included increased cytoplasmic eosin-ophilia in the form of either eosinophilic granules or inclusion bodies, cytoplasmic vacuolization, and marked variation in the size, shape, and intensity of staining of cell nuclei. |
| Databáze: | OpenAIRE |
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