Working memory in middle-aged males: age-related brain activation changes and cognitive fatigue effects
| Autor: | Renate H. M. de Groot, Elisabeth A. T. Evers, Dick J. Veltman, Elissa B. Klaassen, Walter H. Backes, Jelle Jolles |
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| Přispěvatelé: | Neuropsychology & Psychopharmacology, Psychiatrie & Neuropsychologie, RS: FPN NPPP II, Educational Neuroscience, Neuroscience Campus Amsterdam - Neurobiology of Mental Health, LEARN! - Brain, learning and development, RS-Research Line Fostering Effective, Efficient and Enjoyable Learning (FEEEL) (part of WO program), RS-Research Program Welten Onderzoeksprogramma (WO), Psychiatry, NCA - Neurobiology of mental health |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Brain activation
Adult Male medicine.medical_specialty Aging Visual Analog Scale Functional magnetic resonance imaging Audiology Neuropsychological Tests Age related medicine Image Processing Computer-Assisted Humans Young adult Analysis of Variance Memory Disorders medicine.diagnostic_test Working memory General Neuroscience Superior parietal cortex Age Factors Brain Cognition Dorsomedial prefrontal cortex Middle Aged Mental Fatigue Magnetic Resonance Imaging Cognitive fatigue Oxygen Neuropsychology and Physiological Psychology Memory Short-Term Psychology Neuroscience |
| Zdroj: | Biological Psychology, 96, 134-143. Elsevier Science Biological Psychology, 96, 134-143. Elsevier Klaassen, E B, Evers, E A T, Groot, R H M, Backes, W H, Veltman, D J & Jolles, J 2014, ' Working memory in middle-aged males: age related brain activation changes and cognitive fatigue effects ', Biological Psychology, vol. 96, pp. 134-143 . https://doi.org/10.1016/j.biopsycho.2013.11.008 Klaassen, E B, Evers, E A T, De Groot, R, Backes, W H, Veltman, D J & Jolles, J 2014, ' Working memory in middle-aged males: Age-related brain activation changes and cognitive fatigue effects ', Biological Psychology, vol. 96, pp. 134-143 . https://doi.org/10.1016/j.biopsycho.2013.11.008 |
| ISSN: | 0301-0511 |
| DOI: | 10.1016/j.biopsycho.2013.11.008 |
| Popis: | We examined the effects of aging and cognitive fatigue on working memory (WM) related brain activation using functional magnetic resonance imaging. Age-related differences were investigated in 13 young and 16 middle-aged male school teachers. Cognitive fatigue was induced by sustained performance on cognitively demanding tasks (compared to a control condition). Results showed a main effect of age on left dorsolateral prefrontal and superior parietal cortex activation during WM encoding; greater activation was evident in middle-aged than young adults regardless of WM load or fatigue condition. An interaction effect was found in the dorsomedial prefrontal cortex (DMPFC); WM load-dependent activation was elevated in middle-aged compared to young in the control condition, but did not differ in the fatigue condition due to a reduction in activation in middle-aged in contrast to an increase in activation in the young group. These findings demonstrate age-related activation differences and differential effects of fatigue on activation in young and middle-aged adults. © 2013 Elsevier B.V. |
| Databáze: | OpenAIRE |
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