Acquired cystic disease and renal cell carcinoma in hemodialysis patients--A case report on three patients
| Autor: | Dejan Pilcevic, Brankica Terzic, Novak Milovic, Ljiljana Ignjatovic, Snezana Cerovic, Bozidar Kovacevic, Mirjana Mijuskovic, Katarina Obrencevic, Marijana Petrovic, Jelena Tadić Pilčević, Dara Stefanovic, Dragan Jovanovic |
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| Rok vydání: | 2015 |
| Předmět: |
Nephrology
Adult medicine.medical_specialty Time Factors medicine.medical_treatment Biopsy Urology urologic and male genital diseases Nephrectomy Cystic kidney disease Renal cell carcinoma Predictive Value of Tests Renal Dialysis Risk Factors Internal medicine medicine Carcinoma Humans Pharmacology (medical) Carcinoma Renal Cell Dialysis Aged lcsh:R5-920 Kidney Incidental Findings business.industry hemodyalisis Kidney Diseases Cystic Middle Aged medicine.disease Kidney Neoplasms Surgery medicine.anatomical_structure Treatment Outcome Kidney Failure Chronic Hemodialysis lcsh:Medicine (General) business |
| Zdroj: | Vojnosanitetski Pregled, Vol 72, Iss 10, Pp 932-936 (2015) |
| ISSN: | 0042-8450 |
| Popis: | Introduction. Renal cell carcinoma (RCC) is derived from renal tubular epithelial cells and represents approximately 3.8% of all malignancies in adults. The incidence of renal cell carcinoma has been growing steadily and ranging from 0.6 to 14.7 for every 100,000 inhabitants. Patients with end-stage renal disease and acquired cystic kidney disease are at increased risk of developing RCC while undergoing dialysis treatment or after renal transplantation. Case report. We presented 3 patients undergoing hemodialysis, with acquired cystic kidney disease accompanied by the development of RCC. In all the patients tumor was asymptomatic and discovered through ultrasound screening in 2 patients and in 1 of the patients by post-surgery pathohistological analysis of the tissue of the kidney excised using nephrectomy. All the three patients had organ-limited disease at the time of the diagnosis and they did not require additional therapy after surgical treatment. During the follow- up after nephrectomy from 6 months to 7 years, local recurrence or metastasis of RCC were not diagnosed. Conclusion. Acquired cystic kidney disease represents a predisposing factor for the development of renal cell carcinoma in dialysis patients and requires regular ultrasound examinations of the abdomen aimed at early diagnosis of malignancies. Prognosis for patients with endstage renal disease and RCC is mostly good because these tumors are usually of indolent course. |
| Databáze: | OpenAIRE |
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