The Postoperative C-reactive Protein Level can be a Useful Prognostic Factor for Poor Outcome and Symptomatic Vasospasm in Patients With Aneurysmal Subarachnoid Hemorrhage
| Autor: | Hee Pyoung Park, Hye Kyoung Lee, Jung-Won Hwang, Young Tae Jeon, Hannnah Lee, Ju Hyun Lee, Young Jin Lim |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Subarachnoid hemorrhage Neurosurgical Procedures Postoperative Complications Modified Rankin Scale Internal medicine medicine Humans Vasospasm Intracranial Hospital Mortality cardiovascular diseases Aged Intracerebral hemorrhage biology Receiver operating characteristic business.industry Cerebral infarction C-reactive protein Vasospasm Middle Aged Subarachnoid Hemorrhage Prognosis medicine.disease nervous system diseases Hydrocephalus C-Reactive Protein Treatment Outcome Anesthesiology and Pain Medicine ROC Curve cardiovascular system Cardiology biology.protein Female Surgery Neurology (clinical) business Biomarkers |
| Zdroj: | Journal of Neurosurgical Anesthesiology. 24:317-324 |
| ISSN: | 0898-4921 |
| Popis: | BACKGROUND Ninety-three patients undergoing surgical or endovascular operation secondary to aneurysmal subarachnoid hemorrhage (SAH) were retrospectively analyzed to determine the influence of the different time points of C-reactive protein (CRP) measurement on the prediction of vasospasm and clinical outcome. METHODS Laboratory data such as the CRP level and the white blood cell count, preoperative demographic and clinical data, intraoperative and postoperative data, and complications such as intracerebral hemorrhage, hydrocephalus, vasospasm, and surgical decompression were collected at hospital discharge or symptomatic vasospasm and used as predictable factors for poor outcome (Modified Rankin Scale score 4 to 6). RESULTS Twenty-three and 28 patients showed poor outcome and symptomatic vasospasm after SAH, respectively. Both preoperative and postoperative CRP levels were significantly higher in patients with a poor outcome compared with patients with a good outcome (P |
| Databáze: | OpenAIRE |
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