Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments
| Autor: | Olga Klaudia Szewczyk, Robert Czarnomysy, Krzysztof Bielawski, Dominika Radomska, Piotr Roszczenko |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Drug
Organoplatinum Compounds Combination therapy QH301-705.5 media_common.quotation_subject chemistry.chemical_element Antineoplastic Agents Review palladium complexes Catalysis Inorganic Chemistry 03 medical and health sciences 0302 clinical medicine Neoplasms medicine Animals Humans anticancer treatments Physical and Theoretical Chemistry Biology (General) Molecular Biology QD1-999 Spectroscopy 030304 developmental biology media_common Cisplatin Clinical Trials as Topic 0303 health sciences Organic Chemistry Drug Synergism General Medicine Combinatorial chemistry Computer Science Applications Chemistry chemistry 030220 oncology & carcinogenesis Platinum Palladium medicine.drug platinum complexes |
| Zdroj: | International Journal of Molecular Sciences, Vol 22, Iss 8271, p 8271 (2021) International Journal of Molecular Sciences |
| ISSN: | 1661-6596 1422-0067 |
| Popis: | There is a need for new, safer, and more effective agents to treat cancer. Cytostatics that have transition metals at their core have attracted renewed interest from scientists. Researchers are attempting to use chemotherapeutics, such as cisplatin, in combination therapy (i.e., in order to enhance their effectiveness). Moreover, studies are being carried out to modify molecules, by developing them into multinuclear structures, linking different compounds to commonly used drugs, or encapsulating them in nanoparticles to improve pharmacokinetic parameters, and increase the selectivity of these drugs. Therefore, we attempted to organize recent drug findings that contain palladium and platinum atoms in their structures. |
| Databáze: | OpenAIRE |
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