Histopathological changes in nasal mucosa with nasal septum deviation
| Autor: | Münir Demir Bajin, Rıza Önder Günaydın, Taner Yılmaz, Selçuk Sürücü, Oğuz Kuşçu, Tawakir Kamani |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Adolescent Biopsy medicine.medical_treatment Mucous membrane of nose Young Adult medicine Nasal septum Humans Lymphocytes Sinusitis Nose Nasal Septum Metaplasia business.industry Nose Deformities Acquired Turbinates General Medicine Rhinoplasty medicine.disease Squamous metaplasia Septoplasty Nasal Mucosa medicine.anatomical_structure Otorhinolaryngology Chronic Disease Head and neck surgery Female business |
| Zdroj: | European Archives of Oto-Rhino-Laryngology. 271:2969-2974 |
| ISSN: | 1434-4726 0937-4477 |
| DOI: | 10.1007/s00405-014-2990-x |
| Popis: | Histopathological changes in septal and nasal mucosa of patients with nasal septum deviation are not well known. Biopsies of septal and lateral nasal mucosae from both sides of nose were obtained from 20 patients undergoing septoplasty and control group of 10 patients undergoing head and neck surgery. Histopathological changes including lymphocytic infiltration and squamous metaplasia were compared. This study determined significantly higher rate of squamous metaplasia and lymphocytic infiltration in septal mucosa opposite the deviation compared to control group. Furthermore, there was a significantly higher rate of lymphocytic infiltration in the lateral nasal wall mucosa opposite the deviation when compared to control group. Increased lymphocytic infiltration and squamous metaplasia are observed on both sides of nasal mucosa; however, they are more severe on the side opposite the deviation. Septal deviation predisposes to chronic mucosal inflammation and squamous metaplasia, both of which may render patients susceptible to chronic rhinosinusitis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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