Neutron scattering in the biological sciences: progress and prospects

Autor: Hugh O'Neill, Kushol Gupta, David Fushman, Raquel L. Lieberman, John P. Marino, Edward Lyman, Loukas Petridis, Xiaolin Cheng, Christopher B. Stanley, Frederick Herberle, Yimin Mao, Alexei P. Sokolov, David J.E. Callaway, Yang Zhang, Frank Heinrich, Judith Peters, Robert M. Briber, Xiang-Qiang Chu, Paul W. Fenimore, Liang Hong, Joseph E. Curtis, Flora Meilleur, Jeremy C. Smith, Peter C. E. Moody, Andrey Kovalevsky, William B. O'Dell, Rana Ashkar, Frank Gabel, Mark Dadmun, Norman Wagner, Troy Wymore, Susan Krueger, Michael Weinrich, Kevin L. Weiss, Eugenia Kharlampieva, Hassina Z. Bilheux, Gerald R. Kneller, Mathias Lösche, Ursula Perez-Salas, Heliosa Bordallo, Zvi Kelman, Paul Langan, John Katsaras, Yun Liu, Carla Mattos, Jonathan D. Nickels
Přispěvatelé: Réseaux Innovation Territoires et Mondialisation (RITM), Université Paris-Sud - Paris 11 (UP11), Dept Chem, UnivTennessee, The University of Tennessee [Knoxville], Ctr Biomol Struct & Org, University of Maryland [College Park], University of Maryland System-University of Maryland System, Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Ctr Neutron Res, National Institute of Standards and Technology [Gaithersburg] (NIST), Theorical Division (LANL), Los Alamos National Laboratory (LANL), Computer Engineering Department (Polytechnic School), Universidad de Alcalá - University of Alcalá (UAH), Department of Chemistry [Leicester], University of Leicester, Australian National University (ANU), University of Tennessee System, Centre de biophysique moléculaire (CBM), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Rok vydání: 2018
Předmět:
Zdroj: Acta crystallographica. Section D, Structural biology
Acta crystallographica. Section D, Structural biology, International Union of Crystallography, 2018, 74 (12), pp.1129-1168. ⟨10.1107/S2059798318017503⟩
Acta crystallographica Section D : Structural biology [1993-...]
Acta crystallographica Section D : Structural biology [1993-..], 2018, 74 (12), pp.1129-1168. ⟨10.1107/S2059798318017503⟩
ISSN: 2059-7983
DOI: 10.1107/S2059798318017503⟩
Popis: International audience; The scattering of neutrons can be used to provide information on the structure and dynamics of biological systems on multiple length and time scales. Pursuant to a National Science Foundation-funded workshop in February 2018, recent developments in this field are reviewed here, as well as future prospects that can be expected given recent advances in sources, instrumentation and computational power and methods. Crystallography, solution scattering, dynamics, membranes, labeling and imaging are examined. For the extraction of maximum information, the incorporation of judicious specific deuterium labeling, the integration of several types of experiment, and interpretation using high-performance computer simulation models are often found to be particularly powerful.
Databáze: OpenAIRE
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