The Desire for Amputation or Paralyzation: Evidence for Structural Brain Anomalies in Body Integrity Identity Disorder (BIID)
| Autor: | Guido van Wingen, Judy Luigjes, Rianne M. Blom, H. Steven Scholte, Damiaan Denys, Sija J. van der Wal, Milenna T. van Dijk |
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| Přispěvatelé: | Brein en Cognitie (Psychologie, FMG), Adult Psychiatry, Graduate School, ANS - Compulsivity, Impulsivity & Attention, Netherlands Institute for Neuroscience (NIN) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Central Nervous System
Male Vision Social Sciences lcsh:Medicine Audiology computer.software_genre Nervous System Diagnostic Radiology Cognition 0302 clinical medicine Voxel Cerebellum Parietal Lobe Functional Magnetic Resonance Imaging Medicine and Health Sciences Psychology Gray Matter lcsh:Science media_common Cerebral Cortex Brain Mapping Multidisciplinary medicine.diagnostic_test Radiology and Imaging 05 social sciences Motor Cortex Parietal lobe Brain Middle Aged Body Dysmorphic Disorders Magnetic Resonance Imaging medicine.anatomical_structure Physical body Sensory Perception Female Anatomy Body integrity identity disorder Research Article Adult medicine.medical_specialty Imaging Techniques Brain Morphometry media_common.quotation_subject Neuroimaging Grey matter Research and Analysis Methods Amputation Surgical 050105 experimental psychology Premotor cortex 03 medical and health sciences Diagnostic Medicine Perception Body Image medicine Humans Paralysis 0501 psychology and cognitive sciences Motivation Morphometry lcsh:R Biology and Life Sciences Magnetic resonance imaging medicine.disease Cognitive Science lcsh:Q Voxel-Based Morphometry computer 030217 neurology & neurosurgery Neuroscience |
| Zdroj: | PLoS ONE, Vol 11, Iss 11, p e0165789 (2016) PLoS ONE, 11(11):e0165789. Public Library of Science PLoS ONE, 11(11). Public Library of Science PLoS One, 11(11). Public Library of Science PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | BackgroundBody Integrity Identity Disorder (BIID) is a condition in which individuals perceive a mismatch between their internal body scheme and physical body shape, resulting in an absolute desire to be either amputated or paralyzed. The condition is hypothesized to be of congenital nature, but evidence for a neuro-anatomical basis is sparse.MethodsWe collected T1-weighted structural magnetic resonance imaging scans on a 3T scanner in eight individuals with BIID and 24 matched healthy controls, and analyzed the data using voxel-based morphometry.ResultsThe results showed reduced grey matter volume in the left dorsal and ventral premotor cortices and larger grey matter volume in the cerebellum (lobule VIIa) in individuals with BIID compared to controls.ConclusionThe premotor cortex and cerebellum are thought to be crucial for the experience of body-ownership and the integration of multisensory information. Our results suggest that BIID is associated with structural brain anomalies and might result from a dysfunction in the integration of multisensory information, leading to the feeling of disunity between the mental and physical body shape. |
| Databáze: | OpenAIRE |
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