Synthesis of 3-acylindoles by oxidative rearrangement of 2-aminochalcones using a hypervalent iodine reagent and cyclization sequence
| Autor: | Kazuma Fujimura, Akira Nakamura, Akira Imamiya, Tomohiro Maegawa, Yasuyoshi Miki, Chiaki Ohta, Satoshi Tanaka, Reo Takane |
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| Rok vydání: | 2017 |
| Předmět: |
010405 organic chemistry
Chemistry Organic Chemistry Hypervalent molecule Intramolecular cyclization chemistry.chemical_element Sequence (biology) Oxidative phosphorylation 010402 general chemistry Iodine 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences Reagent Organic chemistry Physical and Theoretical Chemistry |
| Zdroj: | Organic & Biomolecular Chemistry. 15:6702-6705 |
| ISSN: | 1477-0539 1477-0520 |
| DOI: | 10.1039/c7ob01536d |
| Popis: | An efficient one-pot method was developed for the construction of 3-acylindoles via oxidative rearrangement of 2-aminochalcones followed by intramolecular cyclization. The reaction was used to convert a variety of 2-aminochalcones into 3-acylindoles in moderate to high yields. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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