Inhibition of Platelet Function by Uremic Middle Molecules
| Autor: | Bashir Mamdani, Nadine Bazilinski, Emily Czapek, Ashok Patel, George Dunea, Sarosh Ahmed, Mashouf Shaykh |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Blood Platelets
medicine.medical_specialty Platelet Aggregation business.industry Platelet Abnormality medicine.disease Uremia Adenosine diphosphate chemistry.chemical_compound Endocrinology chemistry Biochemistry Sephadex hemic and lymphatic diseases Internal medicine Chromatography Gel medicine Humans Platelet business Ristocetin Function (biology) Uremic middle molecules Toxins Biological |
| Zdroj: | Nephron. 40:423-428 |
| ISSN: | 2235-3186 1660-8151 |
| DOI: | 10.1159/000183512 |
| Popis: | To further define the platelet abnormality responsible for uremic bleeding, we studied platelet aggregation with adenosine diphosphate, ristocetin, and collagen in serum fractions obtained by Sephadex G-15 chromatography. We found that uremic patients had considerable inhibition in several peaks of middle molecular range, but the findings were inconsistent and not clearly related to the degree of uremia. |
| Databáze: | OpenAIRE |
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