Levamisole improves histomorphometric parameters of small intestinal wall of broiler chickens
| Autor: | H. Solhdoost, S. Hamedi, T. Shomali |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty 030106 microbiology levamisole hydrochloride Ileum Biology digestive system histology Jejunum 03 medical and health sciences Intestinal mucosa medicine Potency lcsh:Veterinary medicine broilers General Veterinary digestive oral and skin physiology 0402 animal and dairy science Broiler 04 agricultural and veterinary sciences Levamisole 040201 dairy & animal science Small intestine medicine.anatomical_structure Duodenum lcsh:SF600-1100 medicine.drug |
| Zdroj: | Bulgarian Journal of Veterinary Medicine, Vol 20, Iss 4, Pp 385-391 (2017) |
| ISSN: | 1313-3543 1311-1477 |
| Popis: | Sixty one-day old chickens were divided into 6 equal groups and treated with 0, 2, 5, 10, 15 and 25 mg/kg levamisole from day 1 to 45. Then, all birds sacrificed and samples were taken from duode-num, jejunum and ileum. Cross-sections were made and H&E stained. Histomorphometric parameters including villus height, crypt depth, villus width, sub mucosal width, muscular layer width and the villus height/crypt depth ratio were determined. Duodenal villi became wider in all levamisole treated groups but only the highest dose resulted in taller villi. Jejunal villi became taller without significant change in their width. This was accompanied by a decrease in crypt depth and increased villus height/crypt depth ratio in all treated groups. In ileum, only birds treated with the highest dose had higher villus height, although levamisole at all doses resulted in wider villi. Sub mucosal width in-creased in birds treated with 15 and 25 mg/kg levamisole. In conclusion, levamisole can improve histomorphometric parameters of small intestinal wall of broiler chickens. This can partly explain the mechanism for previously described positive effects of levamisole on performance of broilers. |
| Databáze: | OpenAIRE |
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