Heparin-induced thrombocytopenia during IgA vasculitis: a case report
Autor: | Moe Kyotani, Kaisei Yamasaki, Yoichi Goto, Yasuyo Urase, Tsuneaki Kenzaka |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Immunoglobulin A
medicine.medical_specialty medicine.medical_treatment omcrep/100 Case Report 030204 cardiovascular system & hematology omcrep/2300 Microbiology Gastroenterology omcrep/300 03 medical and health sciences 0302 clinical medicine Heparin-induced thrombocytopenia Internal medicine omcrep/2900 medicine Dialysis 030203 arthritis & rheumatology hemodialysis biology business.industry Heparin medicine.disease omcrep/1100 immunoglobulin A vasculitis omcrep/1000 Purpura Infectious Diseases IgA vasculitis biology.protein Parasitology Hemodialysis medicine.symptom heparin-induced thrombocytopenia Vasculitis business AcademicSubjects/MED00010 edema palpable purpura medicine.drug |
Zdroj: | Oxford Medical Case Reports |
ISSN: | 2053-8855 |
Popis: | Immunoglobulin A (IgA) vasculitis is characterized by small vessel vasculitis involving immune complexes and IgA deposition. The development of heparin-induced thrombocytopenia (HIT) during IgA vasculitis is extremely rare. An 87-year-old man presented with general fatigue, leg edema, purpura, arthritis and renal disease. He was diagnosed with IgA vasculitis and was admitted to our hospital. Hemodialysis with heparin was initiated thrice a week on post-admission Day 11. On Day 21, during hemodialysis, the pressure in the dialysis circuit increased and the dialysis was interrupted. On Day 24, the platelet count rapidly decreased to 18 000/μl. The patient was diagnosed with HIT after testing positive for HIT antibodies; heparin was discontinued at this time. Precautions must be taken against the onset of HIT when initiating hemodialysis in patients with IgA vasculitis. |
Databáze: | OpenAIRE |
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