Hyaline globules reacting positively with zidovudine antibody in brain and spinal cord of AIDS patients

Autor:	B. Bachler, K. Arasteh, F Niedobitek, R. Averdunk, J. Artigas, M. L’age, M. Hornscheidt, G. Grosse
Rok vydání:	1991
Předmět:	Adult Pathology medicine.medical_specialty Central nervous system Antibodies White matter Zidovudine Antibody Specificity medicine Humans Hyaline Brain Chemistry Acquired Immunodeficiency Syndrome Staining and Labeling Hyaline substance business.industry Histology General Medicine Middle Aged Spinal cord Immunohistochemistry medicine.anatomical_structure Spinal Cord Extracellular Space business medicine.drug
Zdroj:	The Lancet. 337:1127-1128
ISSN:	0140-6736
Popis:	Histology of the central nervous system in nine AIDS patients who had been treated with zidovudine showed extracellular hyaline globules in the white matter of the brain and the spinal cord. In immunohistochemical studies with a battery of antibodies, the only positive reaction of these globules was with an antibody to zidovudine. High-performance liquid chromatography showed the presence of a zidovudine isomer in eluates of brain tissue from these patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5b220010da8be06cca515379c81e21 https://doi.org/10.1016/0140-6736(91)92790-9 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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