Usefulness of the ratio of brachial pre-ejection period to brachial ejection time in prediction of cardiovascular and overall mortality in patients with acute myocardial infarction

Autor: Chun-Yuan Chu, Ho-Ming Su, Wei-Chung Tsai, Wen-Hsien Lee, Sheng-Hsiung Sheu, Po-Chao Hsu, Ching-Tang Chang, Wen-Ter Lai, Nai-Yu Chi, Ying-Chih Chen, Tsung-Hsien Lin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Brachial Artery
Physiology
Myocardial Infarction
Blood Pressure
030204 cardiovascular system & hematology
Vascular Medicine
Body Mass Index
0302 clinical medicine
Endocrinology
Medical Conditions
Medicine and Health Sciences
Medicine
030212 general & internal medicine
Myocardial infarction
Multidisciplinary
Hazard ratio
Middle Aged
Pre ejection period
Physiological Parameters
Hypertension
Cardiology
cardiovascular system
Female
Ejection time
Research Article
Cardiac function curve
medicine.medical_specialty
Death Rates
Endocrine Disorders
Systole
Science
03 medical and health sciences
Population Metrics
Predictive Value of Tests
Internal medicine
Diabetes Mellitus
Humans
In patient
Ankle Brachial Index
cardiovascular diseases
Mortality
Aged
Population Biology
business.industry
Body Weight
Biology and Life Sciences
medicine.disease
Confidence interval
Dyslipidemia
Metabolic Disorders
Multivariate Analysis
High ratio
business
Zdroj: PLoS ONE
PLoS ONE, Vol 16, Iss 1, p e0245860 (2021)
ISSN: 1932-6203
Popis: Left ventricular systolic function is a good indicator of cardiac function and a powerful predictor of adverse cardiovascular (CV) outcomes. High ratio of pre-ejection period (PEP) to ejection time (ET) is associated with reduced left ventricular systolic function. Brachial PEP (bPEP) and brachial ET (bET) can be automatically calculated from an ankle-brachial index (ABI)-form device and bPEP/bET was recently reported to be a new and useful parameter of cardiac performance. However, there were no studies evaluating the utility of bPEP/bET for prediction of CV and overall mortality in patients with acute myocardial infarction (AMI). We included 139 cases of AMI admitted to our cardiac care unit consecutively. ABI, bPEP, and bET were obtained from the ABI-form device within the 24 hours of admission. There were 87 overall and 22 CV mortality and the median follow-up to mortality event was 98 months. After multivariable analysis, high bPEP/bET was not only associated with increased long-term CV mortality (hazard ratio (HR) = 1.046; 95% confidence interval (CI): 1.005–1.088; P = 0.029), but also associated with long-term overall mortality (HR = 1.023; 95% CI: 1.001–1.045; P = 0.042). In addition, age was also a significant predictor for CV and overall mortality after the multivariable analysis. In conclusion, bPEP/bET was shown to be a significant predictor for CV and overall mortality in AMI patients after multivariable analysis. Therefore, by means of this novel parameter, we could easily find out the high-risk AMI patients with increased CV and overall mortality.
Databáze: OpenAIRE
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