Acceptability of blood-based HIV self-testing among adolescents aged 15–19 years at risk of HIV acquisition in Bangkok
| Autor: | Thanyawee Puthanakit, Pongpak Phongphiew, Prissana Wongharn, Nantika Paiboon, Juthamanee Moonwong, Surinda Kawichai, Panyaphon Phiphatkhunarnon, Teaka Sowaprux, Wipaporn Natalie Songtaweesin, Patchareeyawan Srimuan |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Adolescent Human immunodeficiency virus (HIV) HIV Infections Dermatology medicine.disease_cause Hiv risk Transgender women Men who have sex with men Sexual and Gender Minorities 03 medical and health sciences 0302 clinical medicine medicine Humans Pharmacology (medical) 030212 general & internal medicine Homosexuality Male Hiv acquisition 030505 public health business.industry Public Health Environmental and Occupational Health Thailand Cross-Sectional Studies Self-Testing Infectious Diseases Female 0305 other medical science business Demography |
| Zdroj: | International Journal of STD & AIDS. 32:927-932 |
| ISSN: | 1758-1052 0956-4624 |
| Popis: | Introduction: Young men who have sex with men (YMSM) and young transgender women (YTGW) in Thailand are at high HIV risk. HIV self-tests (HIVSTs) are rapidly administrable and prompt linkage to HIV treatment or prevention services. This study assesses the acceptability and feasibility of blood-based HIVST use in adolescents. Methods: A cross-sectional study was conducted among YMSM and YTGW aged 15–19 years with HIV acquisition risk. Participants completed questionnaires on the HIVST and then administered INSTI® independently, an HIVST immunoassay detecting gp41 and gp36 antibodies from finger-stick blood. Confirmatory HIV antibody tests were performed. Results: Between July and September 2020, 90 adolescents were enrolled. Mean (SD) age was 17.6 (1.1) years. Half ( N = 45) were YMSM. Forty-six (51%) were first-time HIV testers, and 32 (36%) had “ever used” HIV pre-exposure prophylaxis (PrEP). Two (2.2%, 95% CI: 0.0–5.3) tested positive, 21 (23.4%) invalid, and 67 (74.4%) negative. Invalidity causes included 17 (81%) insufficient blood, 3 (14%) buffer spillage, and 1 (5%) procedural missteps; all had negative HIV antibody tests. HIV self-test acceptability was 87.8% (95% CI: 81.0–94.5). Most (79%) preferred HIVST performance in hospital rather than at home. Conclusions: HIVSTs are acceptable in HIV at-risk adolescents. Blood-based HIVSTs should be positioned as rapid point-of-care tests with real-time linkage to HIV services. |
| Databáze: | OpenAIRE |
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