Effect of sleep on CO2 stimulation of breathing in acute and chronic hypoxia

Autor: Donal J. Reed, Ralph H. Kellogg
Rok vydání: 1960
Předmět:
Zdroj: Journal of Applied Physiology. 15:1135-1138
ISSN: 1522-1601
8750-7587
DOI: 10.1152/jappl.1960.15.6.1135
Popis: The effect of sleep on the respiratory response to graded increases in CO2 was studied in four adult male, sea-level residents during hypoxia at sea level, during 23 days at 14,250 ft. and after return to sea level. One subject was also studied at sea level breathing CO2 mixtures with alternating high and low O2. Hypoxia had no apparent effect on the change in respiratory response to CO2 associated with sleep under any of the conditions studied, but it shifted the curve relating respiratory minute volume to alveolar CO2 tension about 1 mm Hg to the left awake and during sleep. It was concluded that sleep and hypoxia act independently rather than interacting in their effect on the respiratory response to CO2. Submitted on June 6, 1960
Databáze: OpenAIRE