Utility of diffusion-weighted imaging to differentiate benign and malignant solid orbital tumours

Autor: Tejus Pradeep, Advaitaa Ravipati, Samyuktha Melachuri, Fatemeh Rajaii, Ashley A. Campbell, Nickisa Hodgson, Matthew Zhang, Jay J. Pillai, William R. Nunery, Roxana Fu
Rok vydání: 2021
Předmět:
Zdroj: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie.
ISSN: 1715-3360
Popis: We assessed the utility of apparent diffusion coefficients (ADCs) derived from diffusion-weighted imaging to differentiate benign and malignant orbital tumours by oculoplastic surgeons in the clinical setting and sought to validate observed ADC cut-off values.Retrospective review of patients with benign or malignant biopsy-confirmed orbital tumours.Blinded graders including 2 oculoplastic surgeons, 1 neuroradiologist, and 1 medical student located and measured orbital tumour ADCs (10Nonradiologist measurements were compared with each other to assess reliability and with an expert neuroradiologist measurement and final pathology to assess accuracy.Twenty-nine orbital tumours met inclusion criteria, consisting of 6 benign tumours and 23 malignant tumours. Mean ADC values for benign orbital tumours were 1430.59 ± 254.81 and 798.68 ± 309.12 mmOur ADC cut-off of 1120.84 × 10
Databáze: OpenAIRE