Myocardial viability independently influences left ventricular diastolic function in the early phase after acute myocardial infarction
| Autor: | Mariantonietta Cicoira, Loredana Latina, Monica Tinto, Andrea Rossi, Giorgio Golia, Jae K. Oh, Piero Zardini, Maurizio Anselmi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty Wall motion score index Population Left heart catheterization Myocardial Infarction Necrosis Ventricular Dysfunction Left Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Diastolic function Myocardial infarction education Ultrasonography education.field_of_study Ejection fraction Ventricular Remodeling business.industry Myocardium Stroke Volume Middle Aged medicine.disease Preload Cardiology Female Cardiology and Cardiovascular Medicine business Early phase |
| Popis: | Background: After acute myocardial infarction, a broad range of left ventricular (LV) end-diastolic pressure (LVEDP) is expected because of chamber remodeling. However, intrinsic characteristics of the infarcted tissue (necrosis or viability) may also play a role. We aimed to evaluate whether myocardial viability (Mviab) has an influence on LVEDP. Methods: One hundred twenty-three consecutive patients with acute myocardial infarction underwent low-dose dobutamine echocardiography (5-10 μg/kg/min) to assess Mviab. Mviab was quantitatively evaluated by the variation of Δ wall motion score index. Patients underwent left heart catheterization with recording of LVEDP and a complete echocardiographic examination with measurement of LV volumes, ejection fraction, and mass. Results: The overall population (81% male; mean age 58 ± 10 years) was divided into 2 groups according to the presence (group 1; 66 patients) or absence (group 2; 57 patients) of Mviab. LVEDP was higher in patients without Mviab (16 ± 8 vs 20 ± 7 mm Hg; P =.02). The multivariate analysis showed that Δ wall motion score index correlated with LVEDP ( P =.01) independent of wall motion score index and LV end-systolic volume. Conclusions: After acute myocardial infarction, LVEDP shows wide variability and is independently associated with Mviab. (J Am Soc Echocardiogr 2002;15:1490-5.) |
| Databáze: | OpenAIRE |
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