Hypotension and bradycardia after intrathecal ketanserin and phentolamine in the rat
| Autor: | Pramod R. Saxena, K. Mohan Dhasmana, Ajay K. Banerjee |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Male
Bradycardia Ketanserin Hemodynamics Blood Pressure Phentolamine Heart Rate Heart rate Animals Medicine Phenylephrine Injections Spinal Pharmacology business.industry Rats Inbred Strains Spine Rats Vasomotor System Blood pressure Anesthesia Circulatory system Female Hypotension medicine.symptom business circulatory and respiratory physiology medicine.drug |
| Zdroj: | European Journal of Pharmacology. 168:257-260 |
| ISSN: | 0014-2999 |
| DOI: | 10.1016/0014-2999(89)90574-8 |
| Popis: | Intrathecal administration of ketanserin and phentolamine elicited dose-dependent falls in arterial blood pressure and heart rate in anaesthetized rats without attenuation of the pressor responses to i.v. injections of phenylephrine. It is concluded that both ketanserin and phentolamine can decrease arterial blood pressure by acting within the spinal cord. |
| Databáze: | OpenAIRE |
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