Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017

Autor: Plachouras, D., Karki, T., Hansen, S., Hopkins, S., Lyytikainen, O., Moro, M. L., Reilly, J., Zarb, P., Zingg, W., Kinross, P., Weist, K., Monnet, D. L., Suetens, C., Strauss, R., Presterl, E., Latour, K., Vandael, E., Dobreva, E., Ivanov, I. N., Budimir, A., Bosnjak, Z., Hadjihannas, L., Jindrak, V., Martin, P., Mitt, P., Sarvikivi, E., Daniau, C., Berger-Carbonne, A., Aghdassi, S., Gastmeier, P., Kontopidou, F., Arvaniti, K., Hajdu, A., Gudlaugsson, O., Zotti, C. M., Quattrocolo, F., Burns, K., Dimina, E., Vilde, A., Staniulyte, J., Debacker, M., Arendt, V., Borg, M. A., Hopmans, T., Smid, E., Berg, T. C., Alberg, T., Deptula, A., Rydygier, L., Neves, I., Pacheco, P., Serban, R. I., Niculcea, A. S., Markovic-Denic, L., Dragovac, G., Litvova, S., Stefkovicova, M., Zupanc, T. L., Korosec, A., Asensio, A., Cantero, M., Johnson, A., Sartaj, M., Mcconaghy, M., Cairns, S., Gibbons, C., Nedyalkov, M., Hristova, R., Harrison, W., Florentin, D.
Přispěvatelé: Latour, Katrien, Vandael, Eline, Point Prevalence Survey Study Group
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Author's Correction
0301 basic medicine
Male
Epidemiology
Respiratory Tract Infections/drug therapy/epidemiology
Anti-Infective Agents/therapeutic use
antibiotic use
0302 clinical medicine
Anti-Infective Agents
Antibiotics
Acute care
Surveys and Questionnaires
Antimicrobial stewardship
Pseudomonas aeruginosa infections
030212 general & internal medicine
Respiratory Tract Infections
Tuberculosis -- Case studies
media_common
Cross Infection
Respiratory tract infections
Drug Utilization/statistics & numerical data
Hospitals/statistics & numerical data
Penicillins/therapeutic use
Antimicrobial
Hospitals
Community-Acquired Infections/drug therapy/epidemiology
3. Good health
Community-Acquired Infections
Intensive Care Units
healthcare-associated infections
surveillance
Anti-infective agents
Infection -- Control
Female
beta-Lactamase Inhibitors
medicine.medical_specialty
Drug Prescriptions/statistics & numerical data
030106 microbiology
Penicillins
Drug Prescriptions
Beta-Lactamase Inhibitors/therapeutic use
03 medical and health sciences
Surgical prophylaxis
Virology
Cross Infection/drug therapy/epidemiology
point-prevalence survey
medicine
media_common.cataloged_instance
Humans
antimicrobial use
hospitals
European union
Intensive care medicine
Adverse effect
business.industry
Public Health
Environmental and Occupational Health

Drug Utilization
Antimicrobial use
business
Zdroj: Euro Surveillance, Vol. 23, No 46 (2018) pp. 1-14
Eurosurveillance
ISSN: 1025-496X
DOI: 10.2807/1560-7917.es.23.46.1800393
Popis: Antimicrobial agents used to treat infections are lifesaving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms. In 2016–17, we performed the second pointprevalence survey (PPS) of healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals. We included 1,209 hospitals and 310,755 patients in 28 of 31 European Union/European Economic Area (EU/EEA) countries. The weighted prevalence of antimicrobial use in the EU/EEA was 30.5% (95% CI: 29.2–31.9%). The most common indication for prescribing antimicrobials was treatment of a community-acquired infection, followed by treatment of HAI and surgical prophylaxis. Over half (54.2%) of antimicrobials for surgical prophylaxis were prescribed for more than 1 day. The most common infections treated by antimicrobials were respiratory tract infections and the most commonly prescribed antimicrobial agents were penicillins with beta-lactamase inhibitors. There was wide variation of patients on antimicrobials, in the selection of antimicrobial agents and in antimicrobial stewardship resources and activities across the participating countries. The results of the PPS provide detailed information on antimicrobial use in European acute care hospitals, enable comparisons between countries and hospitals, and highlight key areas for national and European action that will support efforts towards prudent use of antimicrobials.
peer-reviewed
Databáze: OpenAIRE