Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress
| Autor: | K Shimizu, Kazuhito Rokutan, Kazunori Suda, K. Miyazaki, Yuki Kuwano, R. Hoshi, Kensei Nishida, Akira Kushiro, Tomoki Igarashi, Akito Kato-Kataoka, O. Watanabe, M. Takada, Mitsuhisa Kawai |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Male Lactobacillus casei Students Medical Cultured Milk Products Physiology Strain (injury) Anxiety Placebo Microbiology Significant elevation law.invention 03 medical and health sciences Probiotic Young Adult 0302 clinical medicine Double-Blind Method law Stress Physiological Medicine Animals Humans Beneficial effects Salivary cortisol biology business.industry Probiotics Tryptophan biology.organism_classification medicine.disease Lacticaseibacillus casei 030104 developmental biology Milk Immunology Fermentation Female medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Beneficial microbes. 7(2) |
| ISSN: | 1876-2891 |
| Popis: | This pilot study investigated the effects of the probiotic Lactobacillus casei strain Shirota (LcS) on psychological, physiological, and physical stress responses in medical students undertaking an authorised nationwide examination for promotion. In a double-blind, placebo-controlled trial, 24 and 23 healthy medical students consumed a fermented milk containing LcS and a placebo milk, respectively, once a day for 8 weeks until the day before the examination. Psychophysical state, salivary cortisol, faecal serotonin, and plasma L-tryptophan were analysed on 5 different sampling days (8 weeks before, 2 weeks before, 1 day before, immediately after, and 2 weeks after the examination). Physical symptoms were also recorded in a diary by subjects during the intervention period for 8 weeks. In association with a significant elevation of anxiety at 1 day before the examination, salivary cortisol and plasma L-tryptophan levels were significantly increased in only the placebo group (P |
| Databáze: | OpenAIRE |
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