Effect of finishing period length with α-tocopherol supplementation on the expression of vitamin E-related genes in the muscle and subcutaneous fat of light lambs
Autor: | Martina Pérez Serrano, Guillermo Ripoll, C. Alberti, Margalida Joy, L. González-Calvo, Jorge H. Calvo, F. Molino |
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Jazyk: | angličtina |
Rok vydání: | 2014 |
Předmět: |
Male
Apolipoprotein E medicine.medical_specialty Peroxisome proliferator-activated receptor gamma Meat medicine.medical_treatment alpha-Tocopherol Biology chemistry.chemical_compound Internal medicine Gene expression Genetics medicine Animals Vitamin E PPARA Gene Tocopherol Muscle Skeletal Sheep food and beverages General Medicine Feeding system Animal Feed Breed Diet Endocrinology chemistry Female lipids (amino acids peptides and proteins) |
Zdroj: | Repositorio de Resultados de Investigación del INIA INIA: Repositorio de Resultados de Investigación del INIA Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA |
Popis: | The aim of this study was to investigate how different finishing period lengths with α-tocopherol supplementation or alfalfa grazing affect mRNA expression levels of genes related to vitamin E metabolism in L. thoracis (LT) muscle and subcutaneous fat (SF) from lambs of the Rasa Aragonesa breed. Indoors, concentrate-fed light lambs (n. =. 48) were supplemented with 500. dl-α-tocopheryl acetate/kg concentrate for an average finishing period length of 0 (C), 10.7 (VE10d), 21.2 (VE20d) and, 32.3 (VE30d) days before slaughtering. Simultaneously, 8 lambs with their dams were alfalfa-grazed. The α-tocopherol affected in a short-term the expression of genes in LT muscle (. ABCA1, LPL, APOE, and SREBP1) and SF (. ABCA1, SCARB1, LPL, and PPARG). On the contrary, PPARA gene expression showed a long-term α-tocopherol effect because the highest levels of PPARA mRNA were found in the VE30d. © 2014 Elsevier B.V. |
Databáze: | OpenAIRE |
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