Pseudomonas aeruginosa tssC1 Links Type VI Secretion and Biofilm-Specific Antibiotic Resistance
| Autor: | Thien-Fah Mah, Aaron Hinz, Jean-Paul Nadeau, Li Zhang |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.drug_class
Antibiotics Microbial Sensitivity Tests Biology Microbial Communities and Interactions medicine.disease_cause Microbiology Antibiotic resistance Bacterial Proteins medicine Secretion Molecular Biology Pseudomonas aeruginosa Biofilm Drug Resistance Microbial biochemical phenomena metabolism and nutrition biology.organism_classification Anti-Bacterial Agents Biofilms Mutation Pseudomonadales Electrophoresis Polyacrylamide Gel Bacteria Pseudomonadaceae |
| Zdroj: | Journal of Bacteriology. 193:5510-5513 |
| ISSN: | 1098-5530 0021-9193 |
| Popis: | Biofilm-specific antibiotic resistance is influenced by multiple factors. We demonstrated that Pseudomonas aeruginosa tssC1 , a gene implicated in type VI secretion (T6S), is important for resistance of biofilms to a subset of antibiotics. We showed that tssC1 expression is induced in biofilms and confirmed that tssC1 is required for T6S. |
| Databáze: | OpenAIRE |
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