Advancement in the chemical analysis of Paeoniae Radix (Shaoyao)
Autor: | Luping Qin, Jinyang Fang, Danni Wei, Binjun Yan, Menglan Shen |
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Rok vydání: | 2018 |
Předmět: |
Molecular Structure
Quantitative nmr Traditional medicine Chemistry Phytochemicals 010401 analytical chemistry Clinical Biochemistry Analytic Sample Preparation Methods Pharmaceutical Science Traditional Chinese medicine Paeonia 030226 pharmacology & pharmacy 01 natural sciences Chemistry Techniques Analytical 0104 chemical sciences Analytical Chemistry 03 medical and health sciences 0302 clinical medicine Paeoniae Radix Qualitative analysis Drug Discovery Evaluation methods Spectroscopy Drugs Chinese Herbal |
Zdroj: | Journal of Pharmaceutical and Biomedical Analysis. 160:276-288 |
ISSN: | 0731-7085 |
Popis: | Paeoniae Radix Alba (baishao or white peony root) and Paeoniae Radix Rubra (chishao or red peony root) are two highly valuable traditional Chinese medicines (TCMs) usually indicated for painful conditions, menstrual disorders and viral infections. These two TCMs are collectively referred to as shaoyao (Paeoniae Radix) due to their close origins and similar chemical compositions. Modern research indicates that monoterpene glycosides, polyphenols and paeonols are the three main types of compounds related to the pharmacological activities of Paeoniae Radix. This review summarizes recent advances in the chemical analysis of Paeoniae Radix and the related traditional Chinese medicine formulas/preparations, including methods used for sample pretreatment, qualitative analysis, quantitative analysis and biological sample analysis. More than 120 papers are discussed in this review, focusing on the chemical analysis of Paeoniae Radix, and various analytical techniques (such as HPLC, LC-MS, IR, near IR and quantitative NMR), as well as their advantages/disadvantages, are described. It is our hope that this paper can provide necessary information for improving the quality evaluation methods currently available for Paeoniae Radix and offer a scientific basis for the future in-depth study of the pharmacokinetics and pharmacodynamics of Paeoniae Radix. |
Databáze: | OpenAIRE |
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