The Inhibitory Circuit Architecture of the Lateral Hypothalamus Orchestrates Feeding

Autor:	Garret D. Stuber, Giorgio Rizzi, Randall L. Ung, Alice M. Stamatakis, Joshua H. Jennings
Rok vydání:	2013
Předmět:	Male medicine.medical_specialty Lateral hypothalamus Neural substrate Hypothalamus Channelrhodopsin Biology Inhibitory postsynaptic potential Eating Mice Glutamatergic Bacterial Proteins Channelrhodopsins Extended amygdala Internal medicine medicine Biological neural network Animals Premovement neuronal activity Obesity GABAergic Neurons gamma-Aminobutyric Acid Multidisciplinary Feeding Behavior Amygdala Adaptation Physiological Mice Mutant Strains Luminescent Proteins Endocrinology Synapses Septal Nuclei Neuroscience
Zdroj:	Science. 341:1517-1521
ISSN:	1095-9203 0036-8075
Popis:	The Overeating Connection Obesity has become a major global health problem. Working in mice, Jennings et al. (p. 1517 ) identified an important brain circuit within the lateral hypothalamus that modulates food intake. The findings reveal the neuronal connections that drive the consumption of highly palatable food even when energy needs are satisfied. Inhibition of this circuit suppressed feeding.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2aa965192379812ba0febbee2511f3 https://doi.org/10.1126/science.1241812 Zobrazit plný text záznamu Plný text ve formátu PDF