Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis

Autor:	Garima NİRMAL, Guruprasad Chellappan SOJAMANİ, Manjusha NAİR, Swapna R. NATH, Priyakumari THANKAMONY
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Complementary and alternative medicine Health Care Sciences and Services Pharmaceutical Science ALL Fusariosis Hemophagocytic Lymphohistiocytosis Pharmacology (medical) Sağlık Bilimleri ve Hizmetleri
Zdroj:	Volume: 12, Issue: 02 69-73 Journal of Microbiology and Infectious Diseases
ISSN:	2146-3158 2146-9369
Popis:	We report here a 7-year girl with B-Acute Lymphoblastic Leukemia (ALL) on Berlin Frankfurt Munster (BFM) based induction chemotherapy who presented with fever, cough, and painful necrotic skin lesions simulating pseudomonas sepsis. The patient was eventually diagnosed with disseminated fusariosis. While on combination antifungal therapy, fever reappeared with pancytopenia and hepatosplenomegaly, and she was subsequently diagnosed with secondary Hemophagocytic lymphohistiocytosis (HLH) and was treated using the HLH 2004 protocol. The child responded to treatment well. This report highlights the high index of clinical suspicion, appropriate investigations needed to diagnose fusariosis and secondary HLH in pediatric oncology practice promptly, and the successful treatment outcome despite having them both.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e230c8b0d3858a3cb94f1826761440e https://dergipark.org.tr/tr/pub/jmid/issue/70259/1130139 Zobrazit plný text záznamu