An Algorithm Informed by the Parathyroid Hormone Level Reduces Hypocalcemic Complications of Thyroidectomy
| Autor: | Michael W. Yeh, Jonathan Bath, James E. Wiseman, Philip H.G. Ituarte, Matthew Mossanen |
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| Jazyk: | angličtina |
| Předmět: |
Male
endocrine system medicine.medical_specialty Cardiac Surgery medicine.medical_treatment Parathyroid hormone Vascular Surgery Peptide hormone Article Postoperative Complications Medicine & Public Health medicine Humans Total thyroidectomy Hypocalcemia business.industry Thyroidectomy Thoracic Surgery nutritional and metabolic diseases Middle Aged medicine.disease Cardiac surgery Abdominal Surgery Hypoparathyroidism Parathyroid Hormone General Surgery Anesthesia Calcium Female Surgery Complication business hormones hormone substitutes and hormone antagonists Algorithms Abdominal surgery |
| Zdroj: | World Journal of Surgery Wiseman, James E.; Mossanen, Matthew; Ituarte, Philip H.; Bath, Jonathan M.; & Yeh, Michael W.(2010). An Algorithm Informed by the Parathyroid Hormone Level Reduces Hypocalcemic Complications of Thyroidectomy. World Journal of Surgery: Official Journal of the International Society of Surgery/Société Internationale de Chirurgie, 34(3), pp 532-537. doi: 10.1007/s00268-009-0348-0. Retrieved from: http://www.escholarship.org/uc/item/4dt2w7b1 |
| ISSN: | 0364-2313 |
| DOI: | 10.1007/s00268-009-0348-0 |
| Popis: | Background Measurement of the parathyroid hormone (PTH) level following total thyroidectomy (TTx) may allow prediction of postoperative hypocalcemia. We present an algorithmic method of managing hypocalcemia pre-emptively, based on the PTH level 1 h after operation. Materials and methods We examined 423 consecutive patients undergoing TTx at a single institution. A subset of patients were managed using an algorithm involving routine postoperative oral calcium administration and the early addition of oral calcitriol in patients with a low 1-h postoperative PTH level. Algorithm patients were compared to a concurrent, conventionally managed group. Outcomes measured included serum calcium levels, symptoms of hypocalcemia, postoperative complications, and receipt of intravenous (IV) calcium. Results The algorithm was applied in 135 patients, and 288 patients were managed conventionally. Critically low calcium levels (total calcium |
| Databáze: | OpenAIRE |
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