Ability of Swept source OCT technology to detect neurodegeneration in patients with type 2 diabetes mellitus without diabetic retinopathy
| Autor: | M. Cipres, Elena García-Martín, Isabel Melchor, Maria Satue, Elisa Vilades, L. Gil-Arribas |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Retinal Ganglion Cells medicine.medical_specialty Ischemia Nerve fiber layer Biomedical Technology Visual Acuity chemistry.chemical_compound Nerve Fibers Diabetes mellitus Ophthalmology Optic Nerve Diseases medicine Humans Ganglion cell layer Intraocular Pressure Aged Diabetic Retinopathy business.industry Retinal Degeneration Type 2 Diabetes Mellitus Retinal General Medicine Diabetic retinopathy Middle Aged medicine.disease eye diseases medicine.anatomical_structure Cross-Sectional Studies chemistry Diabetes Mellitus Type 2 Female sense organs Choroid business Tomography Optical Coherence |
| Zdroj: | Japanese journal of ophthalmology. 64(4) |
| ISSN: | 1613-2246 |
| Popis: | To evaluate neurodegeneration in patients with type 2 Diabetes Mellitus (DM2) without diabetic retinopathy, and to assess the possible role of chronic systemic ischaemia and disease duration in retinal changes. Observational cross sectional study. Sixty eyes of 60 patients with DM2 without signs of diabetic retinopathy (DR), and 60 eyes of 60 healthy controls underwent retinal (ganglion cell layer (GCL), and retinal nerve fiber layer (RNFL) and choroidal evaluation using Swept source Optical coherence tomography, which allows high quality analysis of the different retinal layers and the choroidal plexus. Comparison between patients with presence/absence of systemic vascular complications and different disease duration time was performed. Macular GCL and RNFL were reduced in patients compared to controls (p |
| Databáze: | OpenAIRE |
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