Microfabricated planar glass gas chromatography with photoionization detection
| Autor: | Paul J. Brewer, Martin J. T. Milton, Christopher N. Rhodes, Alastair C. Lewis, Alice Harling, Robin J.P. Grenfell, Gergely Vargha, B. A. Goody, Jacqueline F. Hamilton, Keith D. Bartle, Philip Homewood, Jaydene Halliday |
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| Rok vydání: | 2010 |
| Předmět: |
Volatile Organic Compounds
Resistive touchscreen Chromatography Gas Chromatography Thermoelectric cooling Photochemistry Chemistry Organic Chemistry Temperature Analytical chemistry Equipment Design General Medicine Photoionization Biochemistry Analytical Chemistry law.invention chemistry.chemical_compound Photoionization detector Hydrofluoric acid Optical microscope law Etching Glass Gas chromatography |
| Zdroj: | Journal of Chromatography A. 1217:768-774 |
| ISSN: | 0021-9673 |
| Popis: | We report the development of a microfabricated gas chromatography system suitable for the separation of volatile organic compounds (VOCs) and compatible with use as a portable measurement device. Hydrofluoric acid etching of 95 × 95 mm Schott B270 wafers has been used to give symmetrical hemi-spherical channels within a glass substrate. Two matching glass plates were subsequently cold bonded with the channels aligned; the flatness of the glass surfaces resulted in strong bonding through van der Waals forces. The device comprised gas fluidic interconnections, injection zone and 7.5 and 1.4 m long, 320 μm internal diameter capillaries. Optical microscopy confirmed the capillaries to have fully circular channel profiles. Direct column heating and cooling could be achieved using a combination of resistive heaters and Peltier devices. The low thermal conductivity of glass allowed for multiple uniform temperature zones to be achieved within a single glass chip. Temperature control over the range 10–200 °C was achieved with peak power demand of approximately 25 W. The 7.5 m capillary column was static coated with a 2 μm film of non-polar dimethylpolysiloxane stationary phase. A standard FID and a modified lightweight 100 mW photoionization detector (PID) were coupled to the column and performance tested with gas mixtures of monoaromatic and monoterpene species at the parts per million concentration level. The low power GC-PID device showed good performance for a small set of VOCs and sub ng detection sensitivity to monoaromatics. |
| Databáze: | OpenAIRE |
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