| Autor: |
Julia A. Balfour, Malini Haria |
| Rok vydání: |
1997 |
| Předmět: |
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| Zdroj: |
CNS Drugs. 7:159-164 |
| ISSN: |
1172-7047 |
| DOI: |
10.2165/00023210-199707020-00006 |
| Popis: |
[Symbol: see text] Levetiracetam is an ethyl analogue of the nootropic agent piracetam.[Symbol: see text] Results from rodent studies indicate that the drug may offer protection against absence, generalised and partial seizures.[Symbol: see text] Levetiracetam exhibits linear pharmacokinetics and has a wide therapeutic index. Its potential to interact with other anticonvulsants appears to be low.[Symbol: see text] Initial findings from a total of 29 patients with treatment-refractory epilepsy suggest that levetiracetam may be beneficial in patients with partial seizures. These results require confirmation.[Symbol: see text] Somnolence and asthenia were the most common adverse events reported in patients receiving levetiracetam 1000 to 4000 mg/day; these appeared to be dose-related. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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