SOX5 promotes cell growth and migration through modulating the DNMT1/p21 pathway in bladder cancer

Autor: Longxiang Wu, Zhongqing Yang, Guoyu Dai, Benyi Fan, Junbin Yuan, Yalin Liu, Peihua Liu, Zhenyu Ou
Rok vydání: 2022
Předmět:
Zdroj: Acta biochimica et biophysica Sinica. 54(7)
ISSN: 1745-7270
Popis: Bladder cancer (BC) is one of the most prevalent and life-threatening cancers among the male population worldwide. Sex determining region Y-box protein 5 (SOX5) plays important roles in a variety of human cancers. However, little research has been conducted on the function and underlying mechanism of SOX5 in BC. In the present study, we first reveal the increased expression of SOX5 in BC tissues and
Databáze: OpenAIRE