Survival and complications with a surgical approach in advanced hypopharyngeal cancer
| Autor: | Maria Paz Galeano Machuca, Deborah L. Ng, Shyuang‐Der Terng, Chih-Tao Cheng, Wen‐Ching Wu |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Taiwan Kaplan-Meier Estimate Disease-Free Survival 03 medical and health sciences Postoperative Complications 0302 clinical medicine Swallowing Pharyngeal cancer Overall survival Humans Medicine Registries Stage (cooking) Propensity Score Aged Neoplasm Staging Hypopharyngeal Neoplasms Surgical approach Squamous Cell Carcinoma of Head and Neck business.industry Nationwide database Hypopharyngeal cancer General Medicine Middle Aged medicine.disease Cancer treatment Surgery Oncology 030220 oncology & carcinogenesis Neck Dissection Female 030211 gastroenterology & hepatology business |
| Zdroj: | Journal of Surgical Oncology. 123:1540-1546 |
| ISSN: | 1096-9098 0022-4790 |
| Popis: | BACKGROUND AND OBJECTIVES The treatment paradigm for advanced hypopharyngeal cancer has shifted from surgical approaches to organ preservation. However, recent studies indicated that surgical approaches may be associated with better survival rates. This study aimed to conduct a head-to-head comparison of survival outcomes and complications with surgical versus nonsurgical approaches using a nationwide database. METHODS Using a nationwide data set, we gathered 2196 propensity score-matched patients with stage III/IVa hypopharyngeal cancer. We compared survival rates and complications among patients with surgical and nonsurgical cancer treatment. RESULTS Patients with stage III and IVa hypopharyngeal cancer who underwent initial surgery had significantly better 5-year overall survival and disease-free survival rates compared to their nonsurgical counterparts. There were no significant differences in long-term complications with regard to swallowing. CONCLUSIONS These results suggest that patients who underwent initial surgery for advanced hypopharyngeal cancers had better survival rates and equivalent long-term function. |
| Databáze: | OpenAIRE |
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