The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19
| Autor: | Martina Chiurazzi, Mariarosaria Santillo, Barbara De Conno, Simona Damiano, Mauro Cataldi, Bruna Guida, Antonio Colantuoni, Martina Di Maro |
|---|---|
| Přispěvatelé: | Guida, Bruna, Cataldi, Mauro, Santillo, Mariarosaria, Damiano, Simona, DI MARO, Martina, Chiurazzi, Martina, Colantuoni, Antonio, DE CONNO, Barbara |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.drug_class
Physiology Mini Review Inflammation Disease Anti-inflammatory lung angiotensin-converting enzyme 2 Physiology (medical) severe acute respiratory syndrome coronavirus 2 Renin–angiotensin system Medicine QP1-981 nicotinic acetylcholine receptor Lung business.industry Mechanism (biology) medicine.anatomical_structure inflammation Angiotensin-converting enzyme 2 Cholinergic nicotinic acetylcholine receptors medicine.symptom business Neuroscience |
| Zdroj: | Frontiers in Physiology, Vol 12 (2021) Frontiers in Physiology |
| Popis: | The renin angiotensin system and the cholinergic anti-inflammatory pathway have been recently shown to modulate lung inflammation in patients with COVID-19. We will show how studies performed on this disease are starting to provide evidence that these two anti-inflammatory systems may functionally interact with each other, a mechanism that could have a more general physiological relevance than only COVID-19 infection. |
| Databáze: | OpenAIRE |
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