Inflammatory markers IL-1β and RANK-L assessment after non-vital bleaching: A 3-month follow-up
| Autor: | Paulina Ledezma, OB Oliveira, Gustavo Pompermaier Garlet, Francisca Sánchez, Cristian Bersezio, Rolando Vernal, Eduardo Fernández, Juan Estay |
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| Přispěvatelé: | University of Chile, Universidade de São Paulo (USP), Universidade Estadual Paulista (Unesp), Universidad Autónoma de Chile |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Periodontal tissue
genetic structures Bleach 0206 medical engineering Dentistry Color hydrogen peroxide RANK-L 02 engineering and technology Bone resorption 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Tooth Bleaching Medicine Humans Urea Clinical significance Hydrogen peroxide PERÓXIDO DE HIDROGÊNIO Tooth Bleaching Agents General Dentistry business.industry biomarkers 030206 dentistry Hydrogen Peroxide tooth bleaching 020601 biomedical engineering Peroxides chemistry Tooth Discoloration Carbamide peroxide business After treatment Month follow up Follow-Up Studies double-blind study |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Made available in DSpace on 2020-12-12T01:10:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 Fondo Nacional de Desarrollo Científico y Tecnológico Objective: This study assessed IL-1β and RANK-L levels in vivo and color stability of non-vital teeth bleached using hydrogen (35%) and carbamide (37%) peroxides 3 months after treatment. Materials and Methods: Fifty teeth were randomly divided into two groups(n = 25):35% hydrogen peroxide (HP) or 37% carbamide peroxide (CP). Four sessions of intracoronal walking-bleach procedure were performed. IL-1β and RANK-L levels were assessed from gingival crevicular fluid samples (from three vestibular and three palatines sites) at eight different time-points: at the beginning of the study (baseline), after four sessions of intracanal bleaching, and at 1 week, 1 month, and 3 months posttreatment. The color variations were visually detected using Vita bleach shade guide (ΔSGU). Results: Significant increases of IL-1β and RANK-L levels were detected at all time-points (all P 0.8—Spearman) between variables. According the ΔSGU values, a color change of five for HP and four for CP were detected. Conclusions: Non-vital walking bleach technique promotes an increase in IL-1β and RANKL levels in periodontal tissues and also, it is maintained until the third-month posttreatment. Clinical Significance: The internal whitening of teeth increases the levels of cytokines associated with inflammation and bone resorption 3 months after the whitening procedure is finished; this should warn of possible harmful effects of this whitening technique. Department of Restorative Dentistry Faculty of Dentistry University of Chile Department of Conservative Dentistry Faculty of Dentistry University of Chile School of Dentistry of Bauru FOB/USP Departament of Restorative Dentistry Faculty of Dentistry UNESP Instituto de Ciencias Biomédicas Universidad Autónoma de Chile Departament of Restorative Dentistry Faculty of Dentistry UNESP Fondo Nacional de Desarrollo Científico y Tecnológico: 1170575 |
| Databáze: | OpenAIRE |
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