Prognostic Implications of Declining Hemoglobin Content in Patients Hospitalized With Acute Coronary Syndromes
| Autor: | Felice Gragnano, Marco Valgimigli, Michele Franzese, Fabrizio Esposito, Giuseppe Gargiulo, Marisa Avvedimento, Vincenzo Fioretti, Sergio Leonardi, Vanessa Spedicato, Giuseppe Andò, Fabio Magliulo, Paolo Calabrò, Attilio Leone, Martina Scalise, Stephan Windecker, Alessandra Schiavo, Paolo Mazzone, Greta Carrara, Pascal Vranckx, Salvatore Chianese, Giovanni Esposito, Luigi Fimiani, Emanuele Monda, Enrico Frigoli, Dario Di Maio |
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| Přispěvatelé: | Leonardi, S., Gragnano, F., Carrara, G., Gargiulo, G., Frigoli, E., Vranckx, P., Di Maio, D., Spedicato, V., Monda, E., Fimiani, L., Fioretti, V., Esposito, F., Avvedimento, M., Magliulo, F., Leone, A., Chianese, S., Franzese, M., Scalise, M., Schiavo, A., Mazzone, P., Esposito, G., Ando, G., Calabro, P., Windecker, S., Valgimigli, M., Leonardi, Sergio, Gragnano, Felice, Carrara, Greta, Gargiulo, Giuseppe, Frigoli, Enrico, Vranckx, Pascal, Di Maio, Dario, Spedicato, Vanessa, Monda, Emanuele, Fimiani, Luigi, Fioretti, Vincenzo, Esposito, Fabrizio, Avvedimento, Marisa, Magliulo, Fabio, Leone, Attilio, Chianese, Salvatore, Franzese, Michele, Scalise, Martina, Schiavo, Alessandra, Mazzone, Paolo, Esposito, Giovanni, Andò, Giuseppe, Calabrò, Paolo, Windecker, Stephan, Valgimigli, Marco |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Randomization medicine.medical_treatment Hemorrhage 030204 cardiovascular system & hematology acute coronary syndrome 03 medical and health sciences Hemoglobins 0302 clinical medicine Internal medicine medicine Humans In patient 030212 general & internal medicine 610 Medicine & health Aged Aged 80 and over Inpatients business.industry Incidence (epidemiology) Hazard ratio percutaneous coronary intervention Percutaneous coronary intervention Middle Aged hemoglobin medicine.disease Prognosis bleeding Confidence interval Europe Cardiology Female Hemoglobin Cardiology and Cardiovascular Medicine business |
| Popis: | BACKGROUND Contemporary definitions of bleeding endpoints are restricted mostly to clinically overt events. Whether hemoglobin drop per se, with or without overt bleeding, adversely affects the prognosis of patients with acute coronary syndrome (ACS) remains unclear. OBJECTIVES The aim of this study was to examine in the MATRIX (Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of Angiox) trial the incidence, predictors, and prognostic implications of in-hospital hemoglobin drop in patients with ACS managed invasively stratified by the presence of in-hospital bleeding. METHODS Patients were categorized by the presence and amount of in-hospital hemoglobin drop on the basis of baseline and nadir hemoglobin values and further stratified by the occurrence of adjudicated in-hospital bleeding. Hemoglobin drop was defined as minimal ( |
| Databáze: | OpenAIRE |
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