Assay of two 10% (w/v) fipronil spot-on formulations against feline infestations with Ctenocephalides felis
| Autor: | Stéphane Bonneau, Marie-Christine Cadiergues, Josephus J. Fourier |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
Insecticides Veterinary medicine Flea CATS biology Felis Treatment outcome Negative control Cat Diseases biology.organism_classification chemistry.chemical_compound Flea Infestations Treatment Outcome Flea infestation chemistry parasitic diseases Cats Animals Pyrazoles Female Small Animals Ctenocephalides Fipronil |
| Zdroj: | Journal of Feline Medicine and Surgery. 13:304-308 |
| ISSN: | 1532-2750 1098-612X |
| Popis: | A new fipronil-based spot-on formulation was evaluated against experimental flea infestations in cats in two studies. In both studies, eight cats served as negative controls (groups 1 and 4); on day 0, eight cats were treated with a 10% w/v fipronil-based spot-on solution (Effipro Spot-on, 0.5 ml per cat, groups 2 and 5) and eight cats served as positive controls (Frontline Spot-on, 0.5 ml per cat, groups 3 and 6). Each cat was infested on day − 1 with 50 fleas (study 1) and weekly (day 7–day 56) with 100 fleas (study 2). Geometric mean flea counts obtained 48 h after the treatment or each re-infestation were reduced by 99.0 and 98.3% in groups 2 and 3, respectively, on day 2, compared to the negative control group. Cats were protected from re-infestations with an efficacy >99% for 58 days in group 5 and for 37 days in group 6. |
| Databáze: | OpenAIRE |
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