Establishment and multi drug resistance evolution of ST235 Pseudomonas aeruginosa strains in the intensive care unit of a Colombian hospital
| Autor: | Francisco Buelvas, Elena Martinez, Natasha Vanegas, H.W. Stokes, Catalina Tovar, Javier Antonio Escobar Pérez |
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| Rok vydání: | 2014 |
| Předmět: |
IS26
Infecciones bacterianas Antibiotic resistance Hospital acquired infections Farmacorresistencia microbiana Microbial Sensitivity Tests Drug resistance Colombia Biology Integron medicine.disease_cause Microbiology law.invention law Drug Resistance Multiple Bacterial medicine Humans Pseudomonas Infections Insertion sequence Molecular Biology Cross Infection Pseudomonas aeruginosa General Medicine biology.organism_classification Intensive care unit Anti-Bacterial Agents Intensive Care Units Gene cassette biology.protein Pseudomonas aeruginosa ST235 Bacteria |
| Zdroj: | Repositorio U. El Bosque Universidad El Bosque instacron:Universidad El Bosque |
| ISSN: | 0923-2508 |
| Popis: | Drug resistant Pseudomonas aeruginosa represents a therapeutic challenge. To assess the diversity of P. aeruginosa antibiotic resistant variants, isolates were recovered from hospital patients in Colombia. Thirty of 60 isolates contained class 1 integrons and five were of Sequence Type ST235 having appeared in a single intensive care unit. All five possessed an unusual integron but showed differences in gene cassette content and the presence/absence of insertion sequence IS26. This showed that differences can arise rapidly, even within a single ICU. Also, the emergence of IS26 in P. aeruginosa is contributing to the evolution of resistance in this bacterium. |
| Databáze: | OpenAIRE |
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