A Modern Reaffirmation of Surgery as the Optimal Treatment for Solitary Fibrous Tumors of the Pleura
| Autor: | P. Michael McFadden, Elizabeth A. David, Omar Toubat, Scott M. Atay, Li Ding, Mimi J. Yao, Anthony W. Kim, Peggy J. Ebner |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Solitary fibrous tumor Time Factors Adolescent 030204 cardiovascular system & hematology Young Adult 03 medical and health sciences Age Distribution 0302 clinical medicine Humans Medicine In patient Sex Distribution Young adult Child Pneumonectomy Aged Neoplasm Staging Retrospective Studies Aged 80 and over Relative survival business.industry Optimal treatment Cancer Retrospective cohort study Middle Aged Prognosis medicine.disease United States Surgery Solitary Fibrous Tumor Pleural Survival Rate Log-rank test 030228 respiratory system Child Preschool Pleura Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | The Annals of Thoracic Surgery. 107:941-946 |
| ISSN: | 0003-4975 |
| DOI: | 10.1016/j.athoracsur.2018.08.069 |
| Popis: | The objective of this study was to identify the most effective treatment for survival in patients with solitary fibrous tumors of the pleura (SFTP).The National Cancer Database was queried for patients with malignant SFTPs. Patients were divided into two groups, those who had surgical treatment and those who did not. The primary outcome was 5-year overall survival, which was assessed by the Kaplan-Meier method and compared using the log rank test.There were 204 patients with SFTPs identified between 2004 and 2014. Of those, 65% of patients (133) had surgical intervention, whereas 18% (37) had no surgical intervention, and 17% (34) had unknown treatment information. Among patients who underwent resection, 42% (56) had sublobar resections, 45% (60) had lobectomies, and 13% (17) had pneumonectomies. The overall 5-year survival for SFTP patients was 56%. Patients who had surgical intervention had a relative survival of 64%, and patients with no surgical intervention had 22% (p0.001). There was no difference in 5-year survival among patients who had sublobar resections compared with patients who had greater anatomic resections (65% versus 64%, p = 0.823).Patients with SFTP who were managed with surgical intervention have better overall survival than patients who are not managed with surgery. Furthermore, similar 5-year survival for sublobar resections compared with greater anatomic resections suggested that the former, when possible, is sufficient. |
| Databáze: | OpenAIRE |
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