Repeated surgeries in invasive lobular breast cancer with preoperative MRI: Role of additional carcinoma in situ and background parenchymal enhancement
Autor: | Benjamin Wiesinger, BM Wietek, Heike Preibsch, Annette Staebler, M Hahn, C. Kloth, Konstantin Nikolaou, Gunnar Blumenstock, SD Bahrs, Vivien Richter, V Hattermann, Georg Bier |
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Rok vydání: | 2017 |
Předmět: |
Adult
Reoperation medicine.medical_specialty medicine.medical_treatment Contrast Media Breast Neoplasms Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer Preoperative Care Parenchyma medicine Humans Mammography Radiology Nuclear Medicine and imaging In patient Breast Mastectomy Parenchymal Tissue Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry Carcinoma in situ Carcinoma Ductal Breast General Medicine Middle Aged Image Enhancement medicine.disease Magnetic Resonance Imaging Carcinoma Lobular 030220 oncology & carcinogenesis Invasive lobular carcinoma Female Histopathology Radiology business Carcinoma in Situ |
Zdroj: | European Journal of Radiology. 90:181-187 |
ISSN: | 0720-048X |
Popis: | Objectives Analysing the influence of additional carcinoma in situ (CIS) and background parenchymal enhancement (BPE) in preoperative MRI on repeated surgeries in patients with invasive lobular carcinoma (ILC) of the breast. Methods Retrospective analysis of 106 patients (mean age 58.6 ± 9.9 years) with 108 ILC. Preoperative tumour size as assessed by MRI, mammography and sonography was recorded and compared to histopathology. In contrast-enhanced MRI, the degree of BPE was categorised by two readers. The influence of additionally detected CIS and BPE on the rate of repeated surgeries was analysed. Results Additional CIS was present in 45.4% of the cases (49/108). The degree of BPE was minimal or mild in 80% of the cases and moderate or marked in 20% of the cases. In 17 cases (15.7%) at least one repeated surgery was performed. In n = 15 of these cases, repeated surgery was performed after BCT (n = 9 re-excisions, n = 6 conversions to mastectomy), in n = 2 cases after initial mastectomy. The initial surgical procedure (p = 0.008) and additional CIS (p = 0.046) significantly influenced the rate of repeated surgeries, while tumour size, patient age and BPE did not (p = ns). Conclusions Additional CIS was associated with a higher rate of repeated surgeries, whereas BPE had no influence. |
Databáze: | OpenAIRE |
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