Reappraisal of Solitary Bronchiolar (Alveolar Cell) Carcinoma of the Lung
| Autor: | R. Nathan Grantham, John A. Mohr, Emery W. Dilling, Edward R. Munnell, Michael R. Harkey |
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| Rok vydání: | 1978 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Pathology medicine.medical_specialty Lung Neoplasms Adenocarcinoma Metastasis Neoplasms Multiple Primary Pulmonary fibrosis Carcinoma Humans Medicine Neoplasm Neoplasm Metastasis Pneumonectomy Survival rate Aged Lung business.industry Adenocarcinoma Bronchiolo-Alveolar Middle Aged medicine.disease Primary tumor Primary Neoplasm medicine.anatomical_structure Female Surgery Neoplasm Recurrence Local Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | The Annals of Thoracic Surgery. 25:289-297 |
| ISSN: | 0003-4975 |
| Popis: | Twelve patients with solitary bronchiolar carcinoma had lobectomy and were followed for up to 16 years. The concept of a multicentric origin of bronchiolar carcinoma, maintained for more than eight decades, should be discarded. The neoplasm arises indolently and usually in an area of pulmonary fibrosis. After lobectomy patients can now expect to follow one of four courses: (1) to be alive and well without recurrence; (2) after several years to have pulmonary recurrence or a new carcinoma; (3) with minute spread at the time of lobectomy to have metastasis develop in a short period; or (4) to die of unrelated conditions. The overall 5-year survival with this tumor is about 75%. Late recurrence or the development of another primary tumor, however, prompts the need for prolonged follow-up. Immunologically, patients have circulating antibodies when well and demonstrable circulating antigens with recurrence. The survival rate of selected patients with solitary bronchiolar carcinoma (eliminating those patients with microscopic spread from the primary neoplasm at the time of resection and those dying of other causes) was 100% after 5 years and 75% after 10 years. |
| Databáze: | OpenAIRE |
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