Inhibition of leukocyte adherence by 3 M potassium chloride extracts of human malignant melanoma
| Autor: | Takuo Sonoda, Albert T. Ichiki, Stephen Krauss, Yvonne P. Quirin |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Male
Cancer Research Pathology medicine.medical_specialty Potassium chemistry.chemical_element Gastroenterology Potassium Chloride Disease course Stable Disease Internal medicine Leukocytes medicine Humans Melanoma business.industry Clinical course Leukocyte Adherence Inhibition Test Middle Aged medicine.disease Leukocyte adherence inhibition test Oncology chemistry Immunologic Techniques Female business |
| Zdroj: | Cancer Letters. 12:259-269 |
| ISSN: | 0304-3835 |
| DOI: | 10.1016/0304-3835(81)90077-x |
| Popis: | The tube leukocyte adherence inhibition (LAI) assay was performed using 3 M KCl extracts of malignant melanoma materials and leukocytes taken from 24 malignant melanoma patients. Of these patients, 21 participated in sequential studies which employed a minimum of 3 time points. An increasing non-adherence index (NAI) was found in 5 of 6 patients who exhibited a favorable disease course. In 5 of 6 patients with an unfavorable disease course, NAI values decreased. In 8 of 9 patients with stable disease, the NAI also was stable. These results indicate that the trend of sequential LAI studies reflects the clinical course of malignant melanoma patients. |
| Databáze: | OpenAIRE |
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