Supplemental Figures and Tables from CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype

Autor: Jonathan R. Brody, Dan A. Dixon, Jordan M. Winter, Paul M. Campbell, Charles J. Yeo, Avinoam Nevler, Cinthya Y. Lowder, Austin Goetz, Eric Londin, Matthew C. Stout, Carmella Romeo, Nicole C. Mambelli-Lisboa, Saswati N. Chand, Ranjan Preet, Mahsa Zarei, Edwin C. Cheung, Shruti Lal
Rok vydání: 2023
Popis: Figure S1: HuR inhibition was successfully achieved by CRISPR/cas9 system. Figure S2: HuR inhibition sensitizes cells to drugs. Figure S3: PDA xenografts with HuR inhibition failed to form tumors. Table S1: Lists the three guide RNAs used to generate CRISPR knockout of HuR in MIA PaCa-2 and Hs 766T cell lines. Table S2: Lists the primers used to detect the mutation created by all three guide RNAs in CRISPR knockout of HuR MIA PaCa-2 and Hs 766T cell lines. Table S3: Lists the clones along with their genotypes obtained for all three guide RNAs.
Databáze: OpenAIRE