Management and response to treatment of Helicobacter pylori gastritis
Autor: | M J Mahony, J I Wyatt, J M Littlewood |
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Rok vydání: | 1992 |
Předmět: |
medicine.medical_specialty
Biopsy Spirillaceae Gastroenterology Helicobacter Infections Sex Factors Internal medicine Gastroscopy Organometallic Compounds Prevalence Gastric mucosa Humans Medicine Prospective Studies Family history Child Prospective cohort study Antibacterial agent Helicobacter pylori biology medicine.diagnostic_test business.industry Age Factors biology.organism_classification medicine.anatomical_structure Socioeconomic Factors Gastric Mucosa Gastritis Pediatrics Perinatology and Child Health Ampicillin Drug Therapy Combination Antacids medicine.symptom business Bismuth Research Article |
Zdroj: | Archives of Disease in Childhood. 67:940-943 |
ISSN: | 1468-2044 0003-9888 |
DOI: | 10.1136/adc.67.7.940 |
Popis: | Gastritis associated with Helicobacter pylori was present in gastric biopsies from 24/95 (25%) children and adolescents undergoing endoscopy for recurrent abdominal pain and upper gastrointestinal symptoms. H pylori associated gastritis occurred mainly in older children (8-16 years) and was significantly associated with low socioeconomic class and a family history of peptic ulcer disease. Antral nodularity was a common endoscopic finding in H pylori positive children. Eighteen children, all over 5 years of age, were treated with tripotassium dicitratobismuthate (De-Nol) for two months and ampicillin for two weeks. In 12 children follow up gastric biopsies were obtained six weeks after completion of treatment. In 9/12 (75%) children H pylori was eradicated, and gastritis improved. |
Databáze: | OpenAIRE |
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