Adult-onset Langerhans cell histiocytosis confined to the skin
| Autor: | S Koran Karadogan, Şükran Tunali, Hakan Turan, S Balaban Adim, Kenan Aydogan |
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| Přispěvatelé: | Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı., Aydoğan, Kenan, Tunalı, S., Karadoğan, Koran S., Adım, Sadiman Balaban, Turan, Hatice Nur, AAH-6216-2021 |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Letter Prednisolone Age of onset Inguinal region Immunofluorescence Dermatology Fluticasone propionate Langerhans cell histiocytosis Skin tumor Case report medicine Skin biopsy Electron microscopy Humans Breast Priority journal Langerhans Cell Histiocytosis Eosinophilic Granuloma Histiocytes Scalp business.industry Deltacortril Cutivate Skin inflammation medicine.disease Immunohistochemistry Skin diseases Infectious Diseases Onset age Skin ulcer Erosion Histiocytosis langerhans-cell Female business Histiocytosis Human |
| Popis: | Langerhans cell histiocytosis (LCH) is a clonal, pleo-morphic disease of unknown aetiology, with theaccumulation of local or disseminated atypical histiocyticcells staining positively for S-100 and CD-1a, and causingdamage in the bones, lungs, mucocutaneous structuresand endocrine organs.1 The condition is generally dia-gnosed in infancy and childhood, but onset in adulthoodcan occasionally occur. The eruption is usually diffuse ormanifests as part of a multisystemic disease, and up to 25–50% of patients with LCH will present initially with acutaneous rash.1–5 Cutaneous manifestations are hetero-genous and similar both in children and adults.1,2 LCHconfined to the skin is uncommon among reported casesof adults.2–8 We describe a rare case of adult-onset LCHpresenting as cutaneous lesions located symmetrically onthe scalp, groin and inframammarian areas, and review theliterature for previous adult cases of isolated cutaneousLCH. |
| Databáze: | OpenAIRE |
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